List of assays available for PDSP Psychoactive Drug Screening Program: B: Binding Assay, F:Functional Assay, *:Under Development, all are cloned except where marked ** Not available *** h:human, m:mouse, r:rat, rab:rabbit Acetylcholine receptors Muscarinic receptor B F h M1 h M2 h M3 h M4 h M5 Nicotinic receptor B   a2/b2 a2/b4 a3/b2 a3/b4 a4/b2 a4/b4 Adenosine receptor B F h ADORA1 h ADORA2A h ADORA2B h ADORA3 Adrenergic receptor B F Alpha 1A Alpha 1B Alpha 1D Alpha 2A Alpha 2B Alpha 2C h Beta1* h Beta2* h Beta3* Angiotensin receptor B   Angiotensin II AT1 Angiotensin II AT2 Cannabinoid B F Cannabinoid 1 Cannabinoid 2 Chemokine F h CCR01 h CCR02 h CCR03 h CCR04 h CCR05 h CCR06 h CCR07 h CCR08 h CCR09 h CCR10 h CCRL1 h CCRL2 Dopamine receptor B F h D1* h D2 r D3 ** h D4 h D5* GABA receptor B   r GABAa ** r GABAb ** r BZP ** GABA BZP(a1) GABA BZP(a2) GABA BZP(a3) GABA BZP(a5) GABA BZP(a6) Glutamate receptor B   r NMDA ** r PCP ** r AMPA *, ** r Kainate*, ** h NR1 h NR2B Metabotropic Glutamate receptor B F mGluR1 mGluRII h mGluR4 r mGluR4 ** h mGluR5a r mGluR5 ** mGluRVI r mGluR7 ** mGluRVIII Endothelial differentiation, lysophosphatidic acid, EDG receptor   F h EDG02 h EDG03 h EDG4 h EDG05 h EDG06 h EDG07 h EDG08 Histamine receptor B F h H1 h H2 h H3* h H4 Imidazoline receptor B   r I1 ** r I2 ** Melanin Concentrating Hormone receptor F h melanin concentrating hormone receptor 1 h melanin concentrating hormone receptor 2 Melanocortin receptor F h MC1 h MC2 h MC3 h MC4 h MC5 Opiate receptor B F DOR KOR MOR ORL-1 Orphan receptor   F h GPR115 h GPR123 h GPR125 h GPR128 h GPR133 h GPR157 h GPR21 h GPR26 h GPR40 h GPR41 h GPR43 h GPR45 h GPR58 h GPR61 h GPR62 h XCR01 Peptide receptor F h C3AR1 complement component 3A h C5L2 h C5R01 h CALCR h CCBP2 h CMKL1 h CMKL2 h CRHR1 h CRHR2 h FPRL1 h FPRL2 h GCGR h GHRHR h GIPR h GLP1R h GLP2R h GLUH1 h HAMEP1 h LTB4R h LTB4R2 h MASS1 h NMUR1 h NMUR2 h Neurotensin NTII h Orexin 2 Oxytocin h PNR h PTHR1 h PTHR2 h SALPR h SCTR h SSTR1 h SSTR2 h SSTR3 h SSTR4 h SSTR5 h TM7SF1 h VIPR2 h UROII urotensin h motilin receptor/GPR38/ghrelin Bradykinin F h BDKRB1 h BDKRB2 Corticotropin Releasing Factor B   CRFR1* CRFR2* Cysteinyl leukotriene F h CLR01 h CLR02 Neurokinin F h NK-1 h NK-2* h NK-3* Neuropeptide Y B F h NPY-Y1* h NPY-Y2* h NPYR4 h NPYR5 Vasopressin receptor B F V1 V2 V3 Prostaglandin receptor B F EP1* rab EP2 EP3 rab EP4 h PTGIR I2 (prostacyclin) Protein Kinase C B   a-PKC b-PKC d-PKC e-PKC g-PKC Purinergic receptor F h P2RY1 h P2RY2 h P2RY4 h P2RY6 h P2RY11 h P2RY12 Serotonin receptor B F h 5HT1A h 5HT1B h 5HT1D h 5HT1E* h 5HT1F* h 5HT2A r 5HT2A ** h 5HT2B h 5-HT2C-INI h 5-HT2C-VGI h 5HT3 h 5HT4* h 5HT5A h 5HT6 h 5HT7A h 5HT7B Transporters B F SERT NET DAT h VMAT1*** h VMAT2*** Others F h EDNRA h EDNRB h EDNRBL h EMR1 h EMR2 h EMR3 h FPR01 h FSK80 h BPZP r Sigma 1 ** r Sigma 2 ** NA+ channel site II *** r CA2+ channel ** HERG MDR-1
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