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| Name: | Wes Kroeze |
| Email: | wkk@case.edu |
| Hometown: | |
| Title: | Research Associate |
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Publications:
Elphick GF, Querbes W, Jordan JA, Gee GV, Eash S, Manley K, Dugan A, Stanifer M, Bhatnagar A, Kroeze WK, Roth BL, Atwood WJ. The human polyomavirus, JCV, uses serotonin receptors to infect cells. Science. 2004 Nov 19;306(5700):1380-3
Bhatnagar A, Sheffler DJ, Kroeze WK, Compton-Toth BA, Roth BL. Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Gaq-coupled GPCRs . J. Biol. Chem. published 9 June 2004, 10.1074/jbc.M404673200
Shapiro DA, Kristiansen K, Weiner DM, Kroeze WK, Roth BL. Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6. J Biol Chem 2002 Mar 29;277(13):11441-9. Epub 2002 Jan 18
Sheffler DJ, Kroeze WK, Garcia BG, Deutch AY, Hufeisen SJ, Leahy P, Bruning JC, Roth BL. p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.. Proc Natl Acad Sci U S A. 2006 Mar 10; [Epub ahead of print]
Roth BL, Sheffler DJ, Kroeze WK. Opinion: Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov. 2004 Apr;3(4):353-9
Kroeze, W.K., K. Kristiansen and BL Roth. Molecular biology of serotonin receptors: structure and function at the molecular level. Curr Top Med Chem 2:507-528, 2002
Kroeze WK, Sheffler DJ, Roth BL. G-protein-coupled receptors at a glance. J Cell Sci 2003 Dec 15;116(Pt 24):4867-9
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